Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-00760 |
IgG1 Fc Protein, Mouse, Recombinant
VH7183,RGD1359539,IgG1,Igh-4 |
Mouse | HEK293 Cells |
Recombinant murine Fc fragment contains the hinge region, CH2, and CH3 region of the mouse IgG1 isotype. IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR) on phagocytic cells with high affinity. Fc fragment is demonstrated to mediate phagocytosis, trigger inflammation, and target Ig to particular tissues. | |||
TMPK-00759 |
IgG1 Fc Protein, Human, Recombinant
Igh-4,VH7183,IgG1,RGD1359539 |
Human | HEK293 Cells |
IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR) on phagocytic cells with high affinity. Fc fragment is demonstrated to mediate phagocytosis, trigger inflammation, and target Ig to particular tissues.IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases. |